4f mph for sale is a new synthetic compound from the group of stimulants, which is a derivative of phenethylamine and piperidine, showing a long-term euphoric and stimulating effect. This compound resembles methylphenidate in its structure, which is an agent used, among other things, in the treatment of attention deficit hyperactivity disorder (ADHD), which is part of drugs such as Concerta or Medikinet. In the United States, 4F-MPH is believed to have been marketed as a replacement for ethylphenidate, which has been under review since April 2015.
Stereoisomers of 4-fluoromethylphenidate (4F-MPH)
4F-MPH for sale is a dopamine reuptake inhibitor with greater potency than methylphenidate. Stereoisomers (compounds with the same way of connecting atoms, but differing in spatial arrangement) ±threo-4F-MPH are about 2.5 - 3 times more active than methylphenidate. the ±erythro-4F-MPH stereoisomers are considered inactive. On the other hand, there is a mixture of both of these stereoisomers both in medicinal preparations and in drugs placed on the illegal market.
Reactive dopamine reuptake inhibitor
4F-MPH acts as a dopamine reuptake inhibitor that increases dopamine levels in the brain by binding proteins that transport this neurotransmitter out of the synaptic space. The accumulation of dopamine causes euphoria and intense stimulation. This compound is most often taken orally in powder or tablet form, but it can also be taken intranasally (powder).
doses of 4-fluoromethylphenidate (4F-MPH).
Approximate individual doses of 4F-MPH are as follows:
Threshold dose - less than 5 mg;
low dose - 5 - 10 mg;
Average dose - 10 - 15 mg;
High dose - 15 - 20 mg;
Very high dose - over 20 mg.
The time of onset of the first effects in the case of oral consumption is 30 - 60 minutes. from the time of consumption. Time of maximum impact 2 - 4 hours. Shock absorption time 1-2 hours. The occurrence of adverse effects is a period of 5 - 10 hours.
Effects of 4-fluoromethylphenidate (4F-MPH) use
Among the desirable effects of 4F-MPH are: excitement (stimulation), increased concentration, improved ability to perform mental work, acceleration of thought processes, improved perception of musical sensations, increased motivation, euphoria. Side effects include anxiety, depression, irritability, physical and intellectual exhaustion, muscle tremors. People who take 4-fluoromethylphenidate frequently and regularly tend to take more doses compulsively.
Toxic effects, cases of acute poisoning and fatal poisoning
Since 4-fluoromethylphenidate (4F-MPH) is a relatively new compound on the psychoactive drug market, data on its pharmacology and toxicity are limited. In Europe, the first occurrence of 4F-MPH recorded by the Early Warning System of the European Monitoring Center for Drugs and Drug Addiction (EWS EMCDDA) occurred in November 2015. According to Carlier et al. there are reports of numerous poisonings associated with the intake of methylphenidate and its new synthetic analogs. The presence of ethylphenidate was detected in 27 fatal poisonings, in seven of which this compound was identified as the direct cause of death. The data also report one fatality related to the consumption of 3,4-dichloroethylphenidate.
According to Shoff et al. 4-Fluoromethylphenidate was one of the causes of mixed fatal poisonings. Postmortem samples taken from the deceased showed the combined presence of 4-fluoromethylphenidate (4F-MPH), 3-methoxyphencyclidine (3-MeO-PCP), amphetamine, methamphetamine, 6-monoacetylmorphine, morphine, codeine and Δ-9-tetrahydrocannabinol.
Legal status of 4-fluoromethylphenidate (4F-MPH) in Poland
4-Fluoromethylphenidate (4F-MPH) is not included in the lists of psychotropic substances, narcotic substances and new psychoactive substances in the annex to the order of the Minister of Health of August 17, 2018 (Collection of laws from 2018, item 1591, as amended.). In this regulation, the list of psychotropic substances of group II P includes methylphenidate and ethylphenidate.
Buying Etizolam belongs to a class of 'anxiolytics' (anxiety relievers) called benzodiazepines, which are primarily used to treat anxiety disorder, panic disorder and insomnia (difficulty falling or staying asleep). Anxiety is a mental health disorder associated with fear, worry and excessive nervousness. Insomnia is a sleep disorder that causes difficulty falling or staying asleep. Panic disorder is a type of anxiety disorder that causes sudden feelings of fear even when there is no real danger with symptoms such as a fast heartbeat.
In the past, 4-fluoromethylphenidate (4F-MPH) was classified as a substitution agent. In accordance with the order of the Minister of Health of August 21, 2019 amending the order on the list of psychotropic substances, narcotic substances and new psychoactive substances (Collection of laws from 2019, item 1745), which came into force on September 27, 20194 -fluoromethylphenidate (4F-MPH) can, based on the analysis of the chemical structure, be included in the group of new psychoactive substances of the I-NPS group - derivatives of 2-phenethylamine.
Data from the internet forum hyperreal.info on the effectiveness of 4-fluoro-methyl-phenidate (4F-MPH)
High doses of 4-fluoromethylphenidate (4F-MPH)
Feb 25, 2016 post by admas (page 9 of 4-Fluoro-MPH topic):
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